RNA Binding (MicroRNA Targets)

MicroRNA target site predictions from TargetScan v8.0, identifying conserved binding sites across the human transcriptome based on seed sequence complementarity and evolutionary conservation.

Methods

Data in this track hub were uniformly downloaded, processed, and harmonized by FILER2. Raw files were obtained from each source repository, converted to BED/bigBed format, lifted to the target genome assembly where necessary, and annotated with standardized metadata including cell type, tissue category, and assay type.


Data Sources

TargetScan v8

Source: https://www.targetscan.org/vert_80/

Publication: Predicting effective microRNA target sites in mammalian mRNAs

Citation: Agarwal V, Bell GW, Nam JW, Bartel DP. Predicting effective microRNA target sites in mammalian mRNAs. Elife. 2015;4:e05005. Published 2015 Aug 12. doi:10.7554/eLife.05005

Funding: National Institutes of Health (NIH) GM067031 to Vikram Agarwal, George W Bell, Jin-Wu Nam, David P Bartel. Howard Hughes Medical Institute (HHMI) Investigator to David P Bartel. National Science Foundation (NSF) Graduate Research Fellowship to Vikram Agarwal.


References