Activity-by-Contact (ABC) Model

URL: https://www.engreitzlab.org/resources

Publications: Nasser, J., Bergman, D.T., Fulco, C.P. et al. Genome-wide enhancer maps link risk variants to disease genes. Nature 593, 238–243 (2021). https://doi.org/10.1038/s41586-021-03446-x

Funding/Acknowledgements: This work was supported by the Broad Institute (E.S.L.); an NIH Pathway to Independence Award (K99HG009917 and R00HG009917 to J.M.E.); an NHGRI Genomic Innovator Award (R35HG011324 to J.M.E.); the Harvard Society of Fellows (J.M.E.); Gordon and Betty Moore and the BASE Research Initiative at the Lucile Packard Children’s Hospital at Stanford University (J.M.E.); NHGRI P50HG006193 (N.H.); NIDDK P30DK043351 (R.J.X.); NIH U01CA200059 (H.P.); NHGRI U01HG009379, NIMH R01MH101244 and NIMH R37MH107649 (A.K.P.); NIDDK K01DK114379 (H.H.); the Zhengxu and Ying He Foundation, the Stanley Center for Psychiatric Research and NIAID K22AI153648 (J.P.R.); NHGRI U24HG009446 (A.K.); an NSF Graduate Research Fellowship (DGE-1656518 to B.R.D.); and a Siebel Scholarship (F.L.). We thank L. Schweitzer, M. Gentili, M. Biton, C. Smillie, A. Regev, M. Kanai, D. Graham, N. Shoresh, S. Gazal, B. Cleary, R. Cui, P. Rogers, V. Subramanian, G. Schnitzler, R. Gupta, M. Claussnitzer, N. Sinnott-Armstrong, T. Majarian, A. Manning and members of the Lander lab, Hacohen lab and Variant-to-Function Initiative for discussions or technical assistance. This research has been conducted using the UK Biobank Resource.