Javierre 2016 pcHiC

URL: https://osf.io/u8tzp/?view_only=

Publications: Javierre BM, Burren OS, Wilder SP, Kreuzhuber R, Hill SM, Sewitz S, Cairns J, Wingett SW, Várnai C, Thiecke MJ, Burden F, Farrow S, Cutler AJ, Rehnström K, Downes K, Grassi L, Kostadima M, Freire-Pritchett P, Wang F; BLUEPRINT Consortium; Stunnenberg HG, Todd JA, Zerbino DR, Stegle O, Ouwehand WH, Frontini M, Wallace C, Spivakov M, Fraser P. Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters. Cell. 2016 Nov 17;167(5):1369-1384.e19. doi: 10.1016/j.cell.2016.09.037. PMID: 27863249; PMCID: PMC5123897.
 
Funding/Acknowledgements: We thank Stefan Schoenfelder, Takashi Nagano, Stephen Eyre, Jane Worthington, Simon Andrews, and Sach Mukherjee for helpful advice and discussions; Inkyung Jung, Bing Ren, Julia Dmitrieva, and Michel Georges for sharing unpublished observations; and Frank Waldron-Lynch, Helen Stevens, and Marcin Pekalski for provision of the fetal thymus tissue. We thank Nicole Soranzo, the HaemGen consortium, Benjamin Fairfax, and Julian Knight for sharing GWAS and eQTL data. This work was supported by the following grants: UK Medical Research Council (MR/L007150/1, MC_UP_1302/1, MC_UP_1302/3, MC_UP_1302/5), UK Biotechnology and Biological Sciences Research Council (BB/J004480/1), ERC (DEVOCHROMO advanced grant), JDRF (9-2011-253, 5-SRA-2015-130), Wellcome Trust (089989, 091157, 095908, 100140, 107212, 107881), European Union 7th Framework Programme (FP7/2007-2013, grant agreements 241447 [NAIMIT] and 282510 [BLUEPRINT]), NHS Blood and Transplant, NIHR (PG-0310-1002), and BHF (RG/09/12/28096). K.D. is funded by NHS Health Education England. M.F. is supported by the BHF Cambridge Centre of Excellence (RE/13/6/30180). S.P.W., M.K., D.R.Z., and O.S. are funded by the European Molecular Biology Laboratory. We gratefully acknowledge the participation of all NIHR Cambridge BioResource volunteers and thank the NIHR Cambridge BioResource centre and staff for their contribution. Raw data are shared under managed access in accordance with the ethical consent signed by the volunteers. Recall of Cambridge BioResource volunteers is by application. Processed data have been made publicly available as described in STAR Methods.