eQTL gen

URL: http://www.eqtlgen.org/

Publications: Võsa, U., Claringbould, A., Westra, HJ. et al. Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nat Genet 53, 1300–1310 (2021). https://doi.org/10.1038/s41588-021-00913-z

Funding/Acknowledgements: The cohorts participating in this study list their acknowledgements in the cohort-specific sections of the Supplementary Note. This work is supported by a grant from the European Research Council (ERC, ERC Starting Grant agreement number 637640 ImmRisk), a VIDI grant (917.14.374) and a VICI grant from the Netherlands Organisation for Scientific Research (NWO) to L.F. This work has been supported by the European Regional Development Fund and the program Mobilitas Pluss (MOBTP108) to U.Võsa. The project was supported by the ‘De Drie Lichten’ foundation in the Netherlands with a grant to A.C. M.G.N. is supported by ZonMw grants 849200011 and 531003014 from the Netherlands Organisation for Health Research and Development, a VENI grant from the NWO (VI.Veni.191G.030) and a Jacobs Foundation research fellowship. H.Y. is funded by a Diabetes UK RD Lawrence fellowship (17/0005594). This project received funding from the ERC under the European Union’s Horizon 2020 research and innovation program (grant agreement no. 772376 (EScORIAL)) to J.H.V. T.E. and A.K. were supported by the Estonian Research Council grant PRG (PRG1291). A.Battle was supported by NIH grant R01MH109905, NIH grant R01HG008150 (NHGRI; Non-Coding Variants Program) and NIH grant R01MH101814 (NIH Common Fund; GTEx Program). M.G.P.v.d.W. was funded by the Nederlandse Organisatie voor Wetenschappelijk onderzoek, NWO-Veni 192.029. This work was supported by NIH grants R21ES024834 (B.Pierce), R01ES020506 (B.Pierce), R01ES023834 (B.Pierce), R35ES028379 (B.Pierce) and R01CA107431 (H.A.). This work was supported by the Sigrid Juselius Foundation (J.Kettunen) and funds from the Academy of Finland (grant numbers 297338 and 307247) (J.Kettunen) and the Novo Nordisk Foundation (grant number NNF17OC0026062) (J.Kettunen). S.Ripatti was supported by the Academy of Finland Centre of Excellence in Complex Disease Genetics (grant no. 312062). M.G. was supported by EU Horizon 2020 (grant 733100 for SYSCID) and a grant from the Excellence of Science (FNRS and FWO) (grant no. 30770923). We acknowledge support from the BBMRI-NL (Biobanking and Biomolecular Resources Research Infrastructure 184.021.007 and 184.033.111), Spinozapremie (NWO 56-464-14192), the ERC (ERC Advanced 230374) and the KNAW Academy Professor Award (PAH/6635) to D.I.B. G.H. works in a unit that receives funding from the UK MRC (MC_UU_12013/1&2&5) and the University of Bristol. S.B. was supported by the Swiss National Science Foundation (310030-152724). B.M.P. was supported by CHARGE infrastructure grant number HJ105756 for the HVH cohort. This work was supported by the German Federal Ministry of Education and Research (BMBF) within the framework of the e:Med research and funding concept (grant 01ZX1906B) and by LIFE (Leipzig Research Center for Civilization Diseases), Universität Leipzig (which is funded by the European Union, by the European Regional Development Fund and by the Free State of Saxony within the framework of the excellence initiative to H.K. and M.Scholz). We thank the UMCG Genomics Coordination Center, the MOLGENIS team, the UG Center for Information Technology and the UMCG research IT program and their sponsors, in particular the BBMRI-NL for data storage, high-performance computing and web hosting infrastructure. The BBMRI-NL is a research infrastructure financed by the NWO (grant number 184.033.111). We thank K. McIntyre for editing the manuscript text.