Song et. al. chromatin contacts in neural cells

URL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE113483

Publications: Song, M., Yang, X., Ren, X. et al. Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes. Nat Genet 51, 1252–1262 (2019). https://doi.org/10.1038/s41588-019-0472-1

Funding/Acknowledgements: We thank A. Schmitt and B. Ren (Ludwig Institute for Cancer Research, University of California, San Diego) for sharing pcHi-C probes and the pcHi-C protocol. Genomic analysis of the WTC11 line in this study was made possible by the whole-genome sequencing data generated by the Allen Institute for Cell Science. We thank the Institute and its founder P.G. Allen for making this work possible. We thank G. Hon (University of Texas Southwestern Medical Center) and S. Henikoff (Fred Hutchinson Cancer Research Center, Howard Hughes Medical Institute) for providing reagents. We acknowledge the ENCODE Consortium and Bradley Bernstein’s laboratory for generating the ChIP-seq data for astrocytes used in this study. We thank N. Ahituv, Y. Guo, R.D. Hawkins, M. McManus and B. Ren for providing critical feedback on the manuscript. We thank Y. Qu for her contributions to the illustrations for Fig. 1. This work was made possible in part by the Core Grant for Vision Research and the Research to Prevent Blindness Unrestricted Grant no. NIH-NEI P30EY002162. This work was supported by the National Institutes of Health (NIH) grant nos. R01AG057497 (to Y.S., L.G. and H.S.) and R01EY027789 and UM1HG009402 (to Y.S.), the UCSF Weill Institute for Neuroscience Innovation Award, the Hillblom Foundation, and the American Federation for Aging Research New Investigator Award in Alzheimer’s Disease to Y.S., NIH grant nos. R01EY028249, R01HL130533, R01-HL135358 (to B.R.C.), P01NS097206 and U19MH106434 (to H.S.) and R01MH105128, R35NS097370, and U19AI131130 (to G.L.M.). M.S. is supported by NIH grant no. T32GM007175. F.J. is supported by NIH grant no. T32GM007309.