EpiMap

URL: https://compbio.mit.edu/epimap/

Publications: Boix, C.A., James, B.T., Park, Y.P. et al. Regulatory genomic circuitry of human disease loci by integrative epigenomics. Nature 590, 300–307 (2021). https://doi.org/10.1038/s41586-020-03145-z

Funding/Acknowledgements: We thank the ENCODE, Roadmap and GGR consortia for generating high-quality public datasets and rapidly disseminating their results to the broader community; D. Li and T. Wang, and I. Gabdank and J. S. Strattan for making our observed and imputed genome-wide tracks and chromatin-state annotations available through the WashU Epigenome Browser and the ENCODE portal, respectively; J. Ernst for advice, guidance and for developing the ChromImpute methodology and code base; P. Kheradpour for help with the motif enrichment analysis software; L. D. Ward for discussions on interactive visualizations of our predictions and HaploReg; C. Epstein, J. Schreiber, W. Noble, Z. Weng, M. Gerstein, ENCODE, Roadmap, GENCODE and GTEx consortia for feedback on early versions of this work; and I. Jungreis, X. Wang, L. Hou, L. Agudelo, S. Mohammadi, M. Wolf, A. Shi, K. Nguyen, M. Kousi, S. Kuosmanen, E. Schmauch and A. Amirabad for feedback on the work and the resource. This work was supported by the US National Institutes of Health grants HG008155, HG009446, HG009088, HG007234, HG007610, GM113708, MH109978, MH119509 and AG058002 (to M.K.) and the National Institutes of Health training grant GM087237 (to C.A.B.).