README file for the 3DGenome_TAD_bed3_hg38 dataset

I. Description of the dataset
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Data source: 3DGenome
Data source URL: http://3dgenome.fsm.northwestern.edu/publications.html
Genome build: hg38
File format: bed bed3, bgzip-compressed and tabix-indexed
Contents: TAD
Dataset URL: https://tf.lisanwanglab.org/GADB/FILER2/Annotationtracks/3DGenome/TAD/bed3/hg38/
Acknowledgements: http://tf.lisanwanglab.org/GADB/FILER2/acknowledgements/3DGenome.html


II. Dataset version number
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v2_0529_2026	


III. Files in the dataset
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See MANIFEST for the complete file list.

Summary:
- Files: 28 *.bed.gz files
- Auxiliary indexes: giggle_index/


IV. Contributors
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Jeffrey Cifello <Jeffrey.Cifello@pennmedicine.upenn.edu>
Prabhakaran Gangadharan <pganga@pennmedicine.upenn.edu>
Luke Carter <Luke.Carter@pennmedicine.upenn.edu>
Pavel P. Kuksa <pkuksa@pennmedicine.upenn.edu>
Fanny Leung <yyee@pennmedicine.upenn.edu>


V. Workflow description
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Files were processed and standardized using FILER data integration and harmonization pipeline (hipFG).

VI. Input files and Resources
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Original files were obtained from http://3dgenome.fsm.northwestern.edu/publications.html.

VII. File Contents
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1. Example annotation file:
formatted_output_Dixon_2015_H1-ESC_raw_TADs.bed.gz

File schema:
fieldName	sqlType	fieldDescription
chrom	string	Reference sequence chromosome
chromStart	uint	Start position in chromosome, 0-based coordinate system
chromEnd	uint	End position in chromosome

2. Example tabix index file:
formatted_output_Dixon_2015_H1-ESC_raw_TADs.bed.gz.tbi

The annotation track is tabix-indexed to allow efficient retrieval of annotations by chromosome and position.

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Generated from:
- Metadata: https://tf.lisanwanglab.org/FILER2/metadata/filer2.latest.hg38.template
- File schemas: https://tf.lisanwanglab.org/FILER2/metadata/filer2.schemas.latest.tsv
- README template: https://tf.lisanwanglab.org/GADB/metadata/filer.dataset.readme.template
- Generation date: 06/05/2026
